Clayton Custer scored 15 points with four assists and three steals.
Texas A&M was led by Tyler Davis with 24 points.
The Loyola University Ramblers made their first 13 shots of the second half but it was a shot from junior Marques Townes with 6.2 seconds remaining that continued the dream story for the little school that could.
Bench scoring was controlled by Loyola Chicago with 18 points off the bench compared to Nevada's 10 points. Star forward Dean Wade missed the first two games, and played very sparingly in the Sweet 16 win over Kentucky.
Nevada rallied and it came to the final seconds. Part of the proceeds from the bobbleheads will go to the Loyola Athletic Fund and the Sisters Charity of the Blessed Virgin Mary.
Loyola (31-5), which has won three tournament games by a combined four points, faces Kansas State in Saturday's regional final.
Mariah exhorted the Wolf Pack to two come-from-behind wins.
And this squad is inescapably being linked to the 1963 team.
Jerry Harkness, Hunter, John Egan and Rich Rochelle sat together in front-row seats at Philips Arena.
Key storyline: No matter the victor, the Final Four will feature a Cinderella.
While Loyola is making its first NCAA Tournament appearances since 1985, the school has a storied hoops history. This was a conference they won by four games and earned an automatic bid by winning the championship. "They're so resilient and confident", said Moser of his team.
The rout is on at the West Region in Los Angeles.
MI reached the Elite Eight by knocking off Montana, Houston, and Texas A&M. He picked up his third foul midway through the second. Moe Wagner added 21 points and Charles Matthews 18 points for third-seeded MI.
Muhammad-Ali Abdur-Rahkman scored 24 points, Moe Wagner added 21 points and Charles Matthews had 18 points as third-seeded MI had five players in double figures. The Wolverines had eight steals, led by Zavier Simpson with five. In the second half, big-time shots were the difference.
The Seminoles have produced mixed results in dates with MI, losing SU in two of three including an 82-80 loss as 3-point underdogs in their last clash in November 2013.
"It was pretty much, verbatim, the first five minutes of the Tennessee timeout", said Moser, and indeed he was right. But there were more times when they just out-executed Nevada anyway.
Loyola closed the half with a 20-4 run. The Ramblers forced six turnovers by halftime, held Nevada to 33.3 percent shooting on 27 attempts, and held the Wolfpack scoreless for the final seven minutes and 55 seconds of the opening half. Twin brother Cody Martin had 16.
Loyola needed to be nearly ideal to hold off Nevada.
MI guard Muhammad-Ali Abdur-Rahkman had 24 points, seven assists and five rebounds and Moe Wagner had 21 points when the hot-shooting Wolverines advanced to the Elite Eight with a lopsided 99-72 victory over Texas A&M.
All four games in the NCAA Tournament to be played Thursday night involve at least one team seeded seventh or lower. Loyola-Chicago, the 11th seed, defeated Nevada in the last round. In the West, No. 7 seed Texas A&M, fresh off a blowout of 2017 national champion North Carolina, faces No. 3 seed MI.
Kansas State embraces the grind maybe better than anyone in the nation as Bruce Weber's Wildcats claw, scrap, dive, deflect, snatch, and well - grind. So Sister Jean hedged: She filled out another bracket with the Ramblers being eliminated here, in the semifinals of the South Regional. As a result, we'll see an improbable 9 v 11 matchup in the Elite 8.