Buzz It Up News

23andMe DNA kit lets you test breast cancer risk from home


The FDA stresses that despite approving this first-of-its-kind test, the fact is that it only detects three out of 1,000 DNA abnormalities which can lead to cancer, so it shouldn't replace regular mammogram tests or trips to the doctor. For the first time, the agency authorized 23andMe's test for 3 BRCA1/BRCA2 breast cancer mutations, which are most common among Ashkenazi Jews.

According to the National Cancer Institute, the three mutations are present in ~2% of Ashkenazi Jewish women compared to 0 - 0.1% in other populations. "While the detection of a BRCA mutation on this test does indicate an increased risk, only a small percentage of Americans carry one of these three mutations and most BRCA mutations that increase an individual's risk are not detected by this test".

Therefore, you are not completely out of harm's way if you test negative for the 3 mutations. The use of the test carries significant risks if individuals use the test results without consulting a physician or genetic counselor.

The FDA calls the test a "step forward in the availability of DTC genetic tests", but emphasized that there are "a lot of caveats". At MedShadow, she reports on new findings and research on the side effects of prescription drugs.




23andMe founder and CEO Anne Wojcikci acknowledged that most cancer is not hereditary and that this test does not cover many variants tied to an even higher cancer risk. Most cancers are not caused by genetic mutations, and the ones tracked by the test aren't the most common BRCA mutations.

The test should also not be used by consumers or health care providers to decide on any treatments, including anti-hormone therapies and preventive removal of breasts or ovaries. Test results come in the form of a report sent to the user. The test was reviewed through the de novo premarket review pathway. The agency also outlined special controls created to assure test's accuracy and reliability. These special controls, when met along with general controls, provide reasonable assurance of safety and effectiveness for this test.

Topol's warning reflects an FDA letter sent to the service back in 2013, urging 23andMe to discontinue marketing its Saliva Collection Kit and Personal Genome Service.

Related Articles

  • Call of Duty: Black Ops III Updated With New Map and Mode

    Call of Duty: Black Ops III Updated With New Map and Mode

    While it looks legitimate, as always, consider anything that isn't an official confirmation from Activision a rumor. It's rumored this year's COD video game will be Black Ops 4 , although that has yet to be officially confirmed.
    Man kills himself near White House

    Man kills himself near White House

    The incident affected pedestrian and vehicular traffic around the White House, the Secret Service said earlier on Twitter. President Trump and his wife Melania are not now at the White House, instead staying in Florida at the Mar-a-Lago resort.
    WWE RAW Results February 26 - Rowdy Ronda Rousey returns

    WWE RAW Results February 26 - Rowdy Ronda Rousey returns

    Braun Strowman put together the most dominating display in Elimination Chamber history when he eliminated a whopping five superstars.
  • Oculus Rift whiffed, VR fanbois miffed

    Oculus Rift whiffed, VR fanbois miffed

    Oculus co-founder Nate Mitchell confirmed on Twitter that there was an issue affecting the company's Rift headset. Today is the day the Oculus Rift died.
    Mario Tennis Aces, Switch, 3DS Nintendo Direct on for tomorrow

    Mario Tennis Aces, Switch, 3DS Nintendo Direct on for tomorrow

    At this point there's no hard release date, but perhaps Nintendo is ready to give fans a day to circle on their calendars. To see what Nintendo officially has planned, tune in tomorrow at 2:00 pm PT on the official Nintendo Direct website .
    China urges North, South Korea to 'seize opportunity'

    China urges North, South Korea to 'seize opportunity'

    Moon's office is expected to hold a media briefing on the outcome of the visit later Tuesday. Pyongyang will also suspend nuclear tests for as long as the talks are under way.
  • Trump, Merkel concerned over Putin's new weapons

    Trump, Merkel concerned over Putin's new weapons

    Russia's President Vladimir Putin denied accusations that his country intends to spark a new Cold War, NBC News reported. Putin is standing in March 18 elections that polls indicate he should win easily.
    Chris Long defends Lamar Jackson as quarterback

    Chris Long defends Lamar Jackson as quarterback

    Jackson has his flaws, but he is one of the most electrifying playmakers in this year's draft. "It may look like it, but I'm not". The former Louisville standout told the media on Friday at the NFL Combine, that he would not consider a position switch.
    Apple's Next iPhone X Could Be Gigantic

    Apple's Next iPhone X Could Be Gigantic

    The first image, which can be seen above, supposedly shows the display digitizer from Apple's upcoming 6.5-inch iPhone X Plus . Despite the media hype surrounding the iPhone X, Apple saw a disappointing debut for its iPhone sales last quarter.
  • Microsoft Debuts New AI Platform in Windows 10

    Microsoft Debuts New AI Platform in Windows 10

    As part of its latest Developer Day event, Microsoft announced a new AI platform coming in the next version of Windows 10. It is possible to unlock a full version of Windows 10 if you are willing to pay for it.
    No resting on Liverpool's laurels for Klopp

    No resting on Liverpool's laurels for Klopp

    I think this year we belong there [in the quarter-finals] to be honest. We need Adam, 100 per cent, and we will use him for sure".
    Telangana BJP leaders taken into custody

    Telangana BJP leaders taken into custody

    Rao has also stated the call for the front is not against Prime Minister Narenrdra Modi but the slow progress of the country.

Comments