A 5 or "high" chance of severe weather is the NWS's top rating.
Forecasters said the slow-moving front would produce locally heavy rain along the Gulf Coast and in several states in the Southeast and Mid-Atlantic regions.
By about 1:20 p.m., NWS radar had begun picking up storms in western North and SC.
A Hazardous Weather Outlook report also released this morning said some thunderstorms expected this afternoon and evening could produce gusting winds and "marginally severe hail" through 9 p.m. And most of the state of Florida now has a slight risk of severe weather today according to the Storm Prediction Center. From there, the scattered storms will sweep eastward. Lightning is deadly and can strike even well away from the base of a thunderstorm.
Weather threats include damaging wind, hail and possibly a tornado, arriving first in southwestern North Carolina and northern Georgia.
Sampson County spokesman Richard Carr said multiple structures were damaged after a tornado touched down there Tuesday.
NWS: Risk of severe weather for tonight
Mostly sunny skies are expected Thursday with a high in the mid 70s and winds gusting to 20 miles per hour. The tornado caused property damage.
Be on the lookout for flash flooding, as more heavy rain is expected on already saturated ground and swollen rivers.
Officials in a North Carolina county say a possible tornado has damaged an elementary school.
On Friday and Saturday skies will be sunny and temperatures will hover in the 80s.
The Carolinas will need to be weather aware Wednesday as severe weather is likely for the region. Mainly dry now, but we'll see the clouds build, the winds increase and the storms develop later today.